16 Famous Cases Of Actors Who Wouldn’t Collaborate
Hollywood looks glamorous from the outside, but behind the scenes, not everyone gets along like best friends.
Sometimes actors clash so badly on set that they refuse to work together ever again.
These famous feuds have created some of the most talked-about drama in entertainment history, proving that even movie stars are just human.
Disclaimer: All selections and descriptions are based on publicly discussed accounts, media reporting, and opinion rather than verified firsthand testimony or absolute confirmation.
1. Dwayne Johnson and Vin Diesel
Their feud exploded on the set of The Fate of the Furious in 2017.
Johnson posted a cryptic Instagram message calling out unprofessional male co-stars, and everyone knew he meant Diesel.
Though they tried to patch things up privately, the damage was done.
Johnson skipped Fast X entirely, choosing his own spin-off path instead.
2. Julia Roberts and Nick Nolte
During I Love Trouble in 1994, these two couldn’t stand each other.
Roberts called Nolte completely disgusting in interviews, while he labeled her not a nice person.
Director Charles Shyer had to film their scenes separately because the tension was unbearable.
Their chemistry was supposed to drive the romantic comedy, but instead it sank the film.
3. Bill Murray and Lucy Liu
On the Charlie’s Angels set in 2000, Murray allegedly insulted Liu’s acting abilities.
Liu didn’t take the disrespect quietly and stood up for herself immediately.
Their confrontation became so heated that Murray wasn’t asked back for the sequel.
Liu later confirmed the incident, saying she wouldn’t tolerate being treated poorly.
4. Marlon Brando and Frank Sinatra
These legends clashed during Guys and Dolls in 1955.
Sinatra grew frustrated with Brando’s method acting approach, which required multiple takes.
Brando’s tendency to eat during scenes and forget lines drove the perfectionist Sinatra absolutely crazy.
Their different acting styles created constant friction on set.
5. Debra Winger and Shirley MacLaine
Winning an Oscar doesn’t guarantee friendship, as these two proved on Terms of Endearment.
MacLaine allegedly treated Winger poorly, creating a hostile working environment throughout filming.
Winger later admitted their relationship was terrible, filled with resentment and competition.
Despite the film’s critical success, neither actress wanted to relive the experience.
6. Sylvester Stallone and Richard Gere
Before they became superstars, these actors reportedly fought on set.
Their clash happened during an early film project, and the animosity never faded away.
Stallone allegedly threw Gere off a movie set after a heated argument over a scene.
Gere’s rising star power supposedly threatened Stallone’s ego at the time.
7. Shannen Doherty and Alyssa Milano
Their magical sisterhood on Charmed was pure fiction behind the scenes.
Doherty and Milano’s tension became so unbearable that Doherty left after season three.
Milano allegedly gave producers an ultimatum: either Doherty goes or she does.
Doherty later confirmed their relationship was strained from the beginning of the show.
8. Will Smith and Janet Hubert
Aunt Viv’s replacement on Fresh Prince wasn’t just a creative decision.
Hubert accused Smith of getting her fired after she demanded better treatment and pay.
Smith claimed Hubert’s attitude made working conditions difficult for everyone on set.
Their feud lasted nearly three decades, filled with public accusations and bitterness.
However, they finally reconciled during the show’s reunion special in 2020.
9. Ryan Reynolds and Wesley Snipes
Snipes stayed in character as Blade throughout Blade Trinity, even off-camera.
He communicated with Reynolds and others only through Post-it notes signed Blade, creating bizarre tension.
Reynolds later joked about the nightmare production, calling it a challenging experience diplomatically.
10. Bette Davis and Joan Crawford
Their legendary rivalry defined Old Hollywood’s cattiest moments.
During Whatever Happened to Baby Jane?, their mutual hatred actually enhanced their performances perfectly.
Crawford allegedly wore weights under her dress to make Davis hurt her back during a scene.
Davis said terrible things about Crawford in interviews, calling her unprofessional and worse.
11. Bill Murray and Chevy Chase
These comedy legends nearly came to blows backstage at Saturday Night Live.
Chase returned to host after leaving the show, and Murray confronted him about his arrogant attitude.
Their argument turned physical, with cast members having to separate them before punches landed.
Murray allegedly told Chase his face looked like something awful, using colorful language.
12. Charlize Theron and Tom Hardy
The brutal Mad Max: Fury Road shoot tested everyone’s patience, especially theirs.
Theron accused Hardy of being difficult and unprofessional, often arriving late to set.
Hardy’s intense method acting clashed with Theron’s more structured approach to performance.
Director George Miller had to mediate their arguments multiple times during production.
13. Gillian Anderson and David Duchovny
Mulder and Scully’s partnership looked perfect on The X-Files, but reality was complicated.
Anderson and Duchovny barely spoke between takes during early seasons, keeping their distance constantly.
The long shooting schedules and intense pressure created friction that made them avoid each other.
However, unlike most feuds, theirs eventually transformed into genuine friendship over time.
14. Debra Messing and Megan Mullally
Their friendship on Will & Grace seemed unbreakable until the revival changed everything.
Mullally mysteriously stopped appearing in episodes during the final season, sparking immediate speculation.
Sources claimed Messing and Mullally had a falling out so severe they refused scenes together.
Neither actress has publicly explained what happened, maintaining professional silence about the split.
15. Chad Michael Murray and Sophia Bush
(Original text: MasterGracey (talk)), licensed under CC BY 3.0. Via Wikimedia Commons.
Mixing marriage with work rarely ends well, as these One Tree Hill stars discovered.
They married in 2005 but divorced just five months later amid rumors of infidelity.
Despite their split, both had to continue playing romantic interests on the show awkwardly.
Bush later described the marriage as something she wished never happened publicly.
16. Teri Hatcher and the Desperate Housewives Cast
Being left out isn’t just a middle school problem, as Hatcher discovered painfully.
Her Desperate Housewives co-stars reportedly excluded her from cast activities and bonding moments.
The other actresses allegedly presented a gift to the crew but deliberately left Hatcher’s name off.
Hatcher addressed the rumors, saying the situation hurt her deeply but remained vague.
